Disc Medicine Initiates Phase 1b/2 Clinical Study of DISC-0974 in Patients With Myelofibrosis and Severe Anemia

Open-label study will evaluate the potential of DISC-0974, a first-in-class anti-HJV (hemojuvelin) monoclonal antibody, to improve anemia in patients with myelofibrosis DISC-0974 is administered as a subcutaneous injection once a month and is designed to suppress hepcidin, a key contributor to anemia in myelofibrosis and other inflammatory diseases DISC-0974 has previously been shown to decrease … Read more